Tygon<span class="sup">®</span> S-54-HL, Microbore Tubing

Tygon® S-54-HL, Microbore Tubing

Biopharmaceutical Formulation S-54-HL

Introduced in 1964, Tygon® S-54-HL, Microbore Tubing is a variation of S-50-HL that has been stiffened to reduce kinking problems experienced in some applications such as draining blood from the body to a perfusion reservoir.

Tygon® S-54-HL, Microbore Tubing is available in five extremely small sizes for use in catheters, for intravenous or intra-arterial infusion and other surgical and hospital uses. It is stiff enough for easy handling, yet soft enough to reduce problems of puncturing.

Since Tygon® S-54-HL, Microbore Tubing is thermoplastic in nature, it can be fabricated into cannulas or protective sheath products using thermoforming and flaring techniques.

As with Tygon® S-50-HL, an extensive evaluation program assures that Tygon® S-54-HL is qualified to meet or exceed Class VI criteria. A Class VI rating means that the formulation has passed the Class VI test protocol listed in the U.S. Pharmacopeia.

S-54-HL is non-toxic, non-pyrogenic, odorless and non-hemolytic. Its smooth, dense bore prevents build-up and provides outstanding flow characteristics.

Tygon’s exceptional chemical resistance characteristics ideally suit it for sterilizing with any of a wide number of germicides. Completely immerse the tubing in the solution for at least 30 minutes, then flush with a saline solution.

Tygon® tubing may be sterilized in a gas sterilizer using gases based on ethylene oxide. Operation of the gas sterilizer should follow precisely the manufacturer’s recommended procedures.

Tygon® S-54-HL is radiation sterilizable by a cobalt 60 source up to 4 megarads. Tygon® S-54-HL is flexible, but has sufficient rigidity to eliminate danger of wall collapse in suction applications.


  • Clear with a glass-smooth bore
  • Compatible with blood
  • Reduced flexibility for suction applications
  • Lightweight and flexible for easy,
    quick installation
  • Meets USP, Class VI criteria
  • Micro-diameter sizes fit needle gauges 30 to 17
Typical Applications
  • Intravenous and Arterial Infusion
  • Precision Injection and Dispensing Applications


Tygon® S-54-HL Tubing Typical Physical Properties
Property Value or Rating
Color Crystal Clear
Durometer Hardness - Shore A 80
Tensile Strength - psi 2,700
Low Temperature Range Flexible at 10ºF
Brittle at -25ºF
High Temperature Range
Dry Heat
Steam Heat (Autoclave)
30 minutes @ 15 psi
Elongation, % 320%
Odor None
Taste one
Toxicity Non-Toxic

When tested as tubings, values may vary depending on the cross-sectional area tested.